I found that on both computers, it was using all my CPU, and all my RAM. The only thing that fixed it for both computers, was disabling the option to upload in batches. figured I'd put this out there, so that the proper people can look into this. it shouldn't be doing this on high end computers.

Desktop

Windows 8 32-bits

4GB RAM

2GHTz dual core

Laptop

Windows Vista 32-bits

1GB RAM

1.6GHTz dual core

EDIT: Correction. This happens any time files are updated on skydrive from either computer, or from skydrive online. I deleted files from the site, and both computers shot up to 100% CPU, and 100% RAM usage very quickly, even without the option selected.