Dear all, 

I have a very odd problem with a Mac Pro early 2008 model running mountain lion 10.8.4 (12E55). On our network there are other newer macs (imac and macbook pro) running the same software version  of mountain lion that do not experience the same problem. My machine is a clean install, picking up our network setting by DHCP (as with the working machines). It appears to be the same in every aspect of the network config as the working machines. 

The problem:

Outlook 2011 can't access the autoconfigure and manual config fails to communicate with our exchange server (2010 SP1 >rollup 4) and gives the error code -18597. This is because outlook cant access the server correctly. The exchange testing tools passes without a problem (https://www.testexchangeconnectivity.com)  when run on this machine, however when I navigate (with any browser) to https://mail.mydomain/ews/exchange.asmx I get a 403 error and no popup login screen. On all of the other macs the login appears, which indicates that the mac is talking to exchange correctly. This also happens if I run a vm with windows on, indicating that it's not a browser issue. 

I have had my ip address changed (using the second ethernet) just to check that it wasn't something on IT's firewall for my normal IP address, this made no difference.. and I have also used the same physical network port as a 'working' mac, just to make sure that it wasn't something on the switch that I am on. 

I am now totally stuck as to what the problem might be, as it appears to be specific to my mac, rather than a generic problem with macs talking to the exchange server. However, I can't see how this can be the case, unless the exchange server can discriminate between my mac and other macs in some way- it's clearly not an ip address problem as two different ip addresses (one in the 'mac' range on our network and one in the 'pc' range) show the same problem. 

Has anyone any ideas??

Thanks in advance..